• AccuTarget™ Predesigned siRNA Sets


siRNA libraries organized by gene family and function. 25 standard siRNA libraries and 21 fully validated siRNA libraries are available

Bioneer offers the AccuTarget™ Human siRNA Library which contains 25,368 predesigned and manufactured siRNAs for immediate use in your experiments. These Premade human siRNA library is available at 10, 20, 50 and 100 nmole guaranteed yield.. We also offer 25 Pathway specific / gene family siRNA library sets for researchers studying cellular processes, cancer, disease etc. These are available at 0.1, 0.25, 0.5 and 1 nmole guaranteed yield. Finally there are 21 pre-validated siRNA libraries with high knockdown rates and demonstrated effectiveness. Validated siRNAs can be ordered at 10, 20, 50 and 100 nmole guaranteed yield.


Features and Benefits

 

  • Categorized by Pathway / family: Convenient format for research
  • Pre-validated siRNA libraries available: Works the first time and every time
  • Competitive pricing: Great value for your research dollar

]]> Bioneer provides various libraries categorized by gene family and/or pathway. All siRNAs are synthesized in our state-of-the-art clean room facility and then purified free of charge utilizing the company's Bio-RP purification system. Each siRNA is quality controlled by MALDI-TOF mass spectrometry to guarantee highest quality and analyzed by PAGE to confirm its duplex structure. (Figure 1 and 2)



Figure 1. MALDI-TOF mass spectrometry analysis of a custom siRNA. All siRNAs are processed by MALDI-TOF mass spectrometry to ensure its quality.


Figure 2. PAGE data of double-stranded custom siRNA. Complementary single-stranded RNA strands were hybridized to form siRNA duplex and analyzed by 15% non-denaturing PAGE.
SS: single-stranded RNA
DS: double-stranded siRNA               



Figure 3. Knockdown efficiency of AccuTarget™ siRNA Library. To determine the knockdown efficiency, HeLa cells were transfected with individual siRNAs at 100 nM concentration. 24 hours post-transfection, total RNA was isolated and the level of target mRNA was measured by qRT-PCR. This data demonstrates the effectiveness of the Turbo si-Designer algorithm: 83.8% of tested siRNAs induced > 70% knockdown and 38.1% of tested siRNAs elicited > 90% knockdown.



Figure 4. Knockdown efficiency of AccuTarget™ Human Validated Cell Cycle siRNA set. HeLa cells were transfected with individual siRNAs targeting 33 different genes at a concentration of 20 nM. Total RNAs was isolated and the level of target mRNA was measured by qRT-PCR. This data demonstrates the effectiveness of the Turbo si-Designer algorithm.]]> Manual

• siRNA manual


Brochure

• siRNA Products and services


Quality Assurance

Bioneer is the holder of Quality Management System Certificates for the following standards.

• ISO 9001:2008 - certificate

• EN ISO 13485:2003 / AC:2009 - certificate

• EC Directive 98/79/EC - certificate

]]> siRNA Set

Cat. No. Product Description No. of Genes No. of siRNAs Price
SHS-0010 AccuTarget™ Human Antioxidant siRNA Set 38 114 Inquire
SHS-0020 AccuTarget™ Human Apoptosis siRNA Set 290 870 Inquire
SHS-0250 AccuTarget™ Human Cancer siRNA set 1158 3474 Inquire
SHS-0030 AccuTarget™ Human Caspase siRNA set 37 111 Inquire
SHS-0040 AccuTarget™ Human Cell cycle siRNA Set 112 336 Inquire
SHS-0050 AccuTarget™ Human Cyclase siRNA Set 22 66 Inquire
SHS-0060 AccuTarget™ Human Cytochrome P450 siRNA Set 52 156 Inquire
SHS-0070 AccuTarget™ Human Deaminase siRNA Set 22 66 Inquire
SHS-0080 AccuTarget™ Human GPCR signaling pathway siRNA set 732 2196 Inquire
SHS-0090 AccuTarget™ Human Helicase siRNA Set 115 345 Inquire
SHS-0100 AccuTarget™ Human Isomerase siRNA Set 104 312 Inquire
SHS-0110 AccuTarget™ Human Kinase siRNA Set 700 2100 Inquire
SHS-0120 AccuTarget™ Human Ligase siRNA Set 272 816 Inquire
SHS-0130 AccuTarget™ Human Lyase siRNA Set 123 369 Inquire
SHS-0140 AccuTarget™ Human Motor siRNA Set 122 366 Inquire
SHS-0150 AccuTarget™ Human NF-kB pathway siRNA Set 37 111 Inquire
SHS-0160 AccuTarget™ Human Nucleic acid binding siRNA Set 2589 7767 Inquire
SHS-0170 AccuTarget™ Human Oxidoreductase siRNA Set 551 1653 Inquire
SHS-0180 AccuTarget™ Human Peptidase siRNA Set 495 1485 Inquire
SHS-0190 AccuTarget™ Human Phosphatase siRNA Set 188 564 Inquire
SHS-0200 AccuTarget™ Human Receptor siRNA Set 1526 4578 Inquire
SHS-0210 AccuTarget™ Human Transferase siRNA Set 1431 4293 Inquire
SHS-0220 AccuTarget™ Human Transporter siRNA Set 1023 3069 Inquire
SHS-0230 AccuTarget™ Human Tubulin siRNA Set 20 60 Inquire
SHS-0240 AccuTarget™ Human Ubiquitin siRNA Set 77 231 Inquire

siRNA Subset

Cat. No. Product Description No. of Genes No. of siRNAs Price
SHS-0110-1 AccuTarget™ Human AGC Kinase siRNA Subset 58 174 Inquire
SHS-0110-2 AccuTarget™ Human CAMK Kinase siRNA Subset 65 195 Inquire
SHS-0110-3 AccuTarget™ Human CK Kinase siRNA Subset 11 33 Inquire
SHS-0110-4 AccuTarget™ Human CMGC Kinase siRNA Subset 56 168 Inquire
SHS-0110-5 AccuTarget™ Human Other Kinase siRNA Subset 343 1029 Inquire
SHS-0110-6 AccuTarget™ Human STE Kinase siRNA Subset 43 129 Inquire
SHS-0110-7 AccuTarget™ Human TK Kinase siRNA Subset 84 252 Inquire
SHS-0110-8 AccuTarget™ Human TKL Kinase siRNA Subset 40 120 Inquire
SHS-0190-1 AccuTarget™ Human Other Phosphatase siRNA Subset 147 441 Inquire
SHS-0190-2 AccuTarget™ Human Tyrosine Phosphatase siRNA Subset 41 123 Inquire

siRNA Druggable Set

Cat. No. Product Description No. of Genes No. of siRNAs Price
SHD-00XX AccuTarget™ Human Druggable siRNA library set 8175 24,525 Inquire
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